Western blot analysis of extracts from 293 and Hela cells using BCL-XL(Ab-62) antibody.
Western blot analysis of extracts from 293 and Hela cells using BCL-XL(Ab-62) antibody.
BCL2L1 (Ab-62) Antibody
CSB-PA923588
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBCL2L1
Overview
- SupplierCusabio
- Product NameBCL2L1 (Ab-62) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID598
- Target nameBCL2L1
- Target descriptionBCL2 like 1
- Target synonymsapoptosis regulator Bcl-X; BCL2L; bcl-2-like protein 1; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52
- HostRabbit
- IsotypeIgG
- Protein IDQ07817
- Protein NameBcl-2-like protein 1
- Scientific DescriptionPotent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis. Basu A, et.al.( 2003) Mar 13; 538(1-3): 41-7 Cheng E.H.-Y. et.al. (1996) Nature 379:554-556. Sattler M. et.al. (1997), Science 275:983-986. Muchmore S.W.et.al (1996).Nature 381:335-341 Yu J., Zhang L. Mol. (2001)Cell 7:673-682
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203