BCL2L2 Polyclonal Antibody
RD265825A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetBCL2L2
Overview
- SupplierReddot Biotech
- Product NameBCL2L2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID599
- Target nameBCL2L2
- Target descriptionBCL2 like 2
- Target synonymsapoptosis regulator BCL-W; BCL2-L-2; bcl-2-like protein 2; BCLW; BCL-W; PPP1R51; protein phosphatase 1, regulatory subunit 51
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203