BDA-366
HY-101083
Overview
- SupplierMedChem Express
- Product NameBDA-366
- Delivery Days Customer5
- Molecular FormulaC24H29N3O4
- Molecular Weight423.50
- Scientific DescriptionBDA-366 is a potent Bcl2 antagonist ( K i = 3.3 nM), binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells [1] .
- SMILESO=C1C2=C(C(NC[C@H]3CO3)=CC=C2NC[C@H](O)CN(CC)CC)C(C4=CC=CC=C41)=O
- UNSPSC12352200