Bio-Connect

BDA-366

HY-101083
MedChem Express
Molecular Weight423.50
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BDA-366
  • Delivery Days Customer
    5
  • Molecular Formula
    C24H29N3O4
  • Molecular Weight
    423.50
  • Scientific Description
    BDA-366 is a potent Bcl2 antagonist ( K i = 3.3 nM), binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells [1] .
  • SMILES
    O=C1C2=C(C(NC[C@H]3CO3)=CC=C2NC[C@H](O)CN(CC)CC)C(C4=CC=CC=C41)=O
  • UNSPSC
    12352200