Chemical Structure
BE-31405 [158054-02-5]
AG-CN2-0302
Overview
- SupplierAdipoGen Life Sciences
- Product NameBE-31405 [158054-02-5]
- Delivery Days Customer10
- CAS Number158054-02-5
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC28H36O10
- Molecular Weight532.6
- Scientific DescriptionBroad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, C. glabrata and Cryptococcus neoformans. Inhibits the protein synthesis in C. albicans, but not mammalian cells, most probably through elongation factor inhibition. - Chemical. CAS: 158054-02-5. Formula: C28H36O10. MW: 532.6. Isolated from Penicillum minioluyeum. Broad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, Candida glabrata and Cryptococcus neoformans. Inhibits the protein synthesis in Candida albicans, but not mammalian cells, most probably through elongation factor inhibition.
- SMILESC[C@H](CC1)[C@]2([H])[C@]1([H])[C@]3(C=O)[C@](C(C(C)C)=C4)(C(O)=O)[C@]([C@@H]4C3)(CO[C@@]5(O6)O[C@]7([H])[C@@]6([H])O[C@H]([C@@H]5O)[C@H]7OC(C)=O)C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- BE-31405, a new antifungal antibiotic produced by Penicillium minioluteum. I. Description of producing organism, fermentation, isolation, physico-chemical and biological properties: H. Okada, et al.; J. Antibiot. 51, 1081 (1998)
- Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains: K. Nonaka, et al.; J. Antibiot. 68, 573 (2015)