Beauveriolide III [221111-70-2]

TargetMol Chemicals

Beauveriolide III [221111-70-2]

999

Chemical

Research Use Only

Beauveriolide III

C27H41N3O5

487.641

Beauveriolide III is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 microM, as well as inhibits cholesterol synthesis (IC50= 0.41 microM), in primary mouse peritoneal macrophages.1,2Beauveriolide III also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 5.5 microM).2Beauveriolide III (25 and 50 mg/kg) reduces the size of aortic atherosclerotic lesions inLdlr-/-andApoE-/-mouse models of atherosclerosis.

3 years

[H][C@]1(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@]([H])([C@@H](C)CC)C(=O)O1)[C@@H](C)CCCC

-20°C

12352200