Belvarafenib (TFA)

MedChem Express

Belvarafenib (TFA)

10

Research Use Only

99.0

C25H17ClF4N6O3S

592.95

Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively [1] .

O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C.OC(C(F)(F)F)=O

-20°C

12352200