Benzquinamide

Biorbyt

Benzquinamide [63-12-7]

10

63-12-7

Research Use Only

94.86%

C22H32N2O5

404.5

Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzquinamide for alpha2A, alpha2B, and alpha2C adrenergic receptor (alpha2-AR) were 1,365, 691, and 545 nM, respectively. 545 nM, respectively.

CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(C)=O

-20°C

12352200