BET-IN-23 [2953287-57-3]

TargetMol Chemicals

BET-IN-23 [2953287-57-3]

16

Research Use Only

C29H34FN3O5

523.6

BET-IN-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. It exhibits anticancer activity by significantly inhibiting the proliferation of acute myeloid leukemia (AML) cell lines, inducing G0/G1 arrest, and apoptosis in vitro [1].

O(C1=C(C=C(C(C)(C)O)C=C1)C=2C(NCC(=O)N3CCOCC3)=CC(=O)N(C)C2)C4=C(C)C=C(F)C=C4C

-20°C

51202000