beta-Amyloid (12-28) [107015-83-8]

TargetMol Chemicals

beta-Amyloid (12-28) [107015-83-8]

9

107015-83-8

Research Use Only

C89H135N25O25

1955.18

Amyloid beta-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to alpha7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.

[C@@H](CC1=CN=CN1)(NC([C@H](CC2=CN=CN2)NC([C@H](C(C)C)N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(N)=O)=O)CO)=O)=O)C(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)=O)[C@@H](C)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O

-20°C

12352200