beta Amyloid Polyclonal Antibody

Reddot Biotech

beta Amyloid Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Polyclonal

130 ug/ml

Unconjugated

App

amyloid beta (A4) precursor protein

A; Abe; Abeta; Abpp; Adap; Ag; alzheimer disease amyloid A4 protein homolog; amyloid beta A4 protein; amyloid precursor protein; amyloid-beta A4 protein; amyloid-beta precursor protein; amyloidogenic glycoprotein; appican; bet; beta-amyloid precursor protein; betaApp; C; Cvap; E030013M08Rik; protease nexin II

Rabbit

IgG

Abeta derives from APP via proteolytic cleavage by proteases called Oe+/--,beta- and Oe≥-secretase. The Oe+/--secretase cleavage precludes the formation of Abeta,while the beta- and Oe≥-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP),encoded by APP gene which locate on human chromosome 21q,is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth,neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain,kidney,heart and spleen,but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1).

Mouse, Rat

-20°C

12352203