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ProductsBack/beta-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE

beta-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE

Research Use Only

HY-155313

Product group Molecular Biology

Overview

Supplier
MedChem Express
Product Name
beta-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE
Delivery Days Customer
14
Certification
Research Use Only
Scientific Description
beta-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE (compound 20) is auristatins-glucuronide conjugate. Antitumor agent-122 shows in vitro antiproliferative activities against beta-glucuronidase pretreated and untreated cancer cells with an IC50 value of 5.7 nM - 9.7 nM. Antitumor agent-122 shows potent antitumor efficacy in HCT-116 xenograft mouse model without inducing side effects[1].
UNSPSC
41116133