beta-Naphthoflavone-CH2-OH
HY-130269
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Namebeta-Naphthoflavone-CH2-OH
- Delivery Days Customer10
- CertificationResearch Use Only
- Scientific Descriptionbeta-Naphthoflavone-CH2-OH (beta-NF-CH2-OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. beta-Naphthoflavone-CH2-OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., beta-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins [1] .
- UNSPSC41116133