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Betrixaban [330942-05-7]

Betrixaban [330942-05-7]

T4341
TargetMol Chemicals
CAS Number330942-05-7
Product group Chemicals
Estimated Purity99.35%
Molecular Weight451.91
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Betrixaban [330942-05-7]
  • Delivery Days Customer
    9
  • CAS Number
    330942-05-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Betrixaban
  • Estimated Purity
    99.35%
  • Molecular Formula
    C23H22ClN5O3
  • Molecular Weight
    451.91
  • Scientific Description
    Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [4].
  • Shelf life instruction
    3 years
  • SMILES
    COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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