CgoaEWY7QIKER0ytAAAAAD-6Yzc293.png
Betulonaldehyde
T69244
CAS Number4439-98-9
Product group Chemicals
Molecular Weight438.68
Overview
- SupplierTargetMol Chemicals
- Product NameBetulonaldehyde
- Delivery Days Customer44
- CAS Number4439-98-9
- Category SupplierChemical
- Chemical NameBetulonaldehyde
- Molecular FormulaC30H46O2
- Molecular Weight438.68
- Scientific DescriptionBetulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula. It is active against P. falciparum (IC50 = 3.36 ug/ml) and cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s = 19.23 and 17.09 ug/ml, respectively). Topical application of betulonaldehyde (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice. It has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives.
- Shelf life instruction3 years
- SMILESC(=O)[C@]12[C@@]([C@@]3([C@](C)([C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C(=O)CC5)[H])[H])CC1)[H])([C@H](C(C)=C)CC2)[H]
- Storage Instruction-20°
- UNSPSC12352200