BH3I-1

MedChem Express

BH3I-1 [300817-68-9]

10

300817-68-9

Research Use Only

98.0

C15H14BrNO3S2

400.31

BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4+/-0.2 microM in FP assay. BH3I-1 has a Kd of 5.3 microM against the p53/MDM2 pair.

O=C(O)C(C(C)C)N(C/1=O)C(SC1=C\C2=CC=C(Br)C=C2)=S

-20°C,2°C to 8°C

12352200