BI-0252 [1818291-27-8]

TargetMol Chemicals

BI-0252 [1818291-27-8]

86

1818291-27-8

Chemical

Research Use Only

BI-0252

C30H26Cl2FN3O3

566.45

BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.

3 years

C(N1[C@@]2([C@H]([C@]3([C@@]1(C[C@@H](N3)C4=CC=C(C(O)=O)C=C4)[H])[H])C5=C(F)C(Cl)=CC=C5)C=6C(NC2=O)=CC(Cl)=CC6)C7CC7

-20°C

12352200