BI-135585

MedChem Express

BI-135585 [1114561-85-1]

10

1114561-85-1

Research Use Only

C28H32N2O4

460.56

BI-135585 is a potent, selective and orally active 11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1) inhibitor with an IC 50 of 13 nM. BI-135585 exhibits >1000-fold selectivity over other hydroxysteroid dehydrogenases. BI-135585 can be used for type 2 diabetes research [1] [2] .

CC(C)(O)C[C@@]1(C2=CC=CC=C2)OC(N(CC1)[C@H](C3=CC=C(C4=CC(N(C=C4)C)=O)C=C3)C)=O

12352200