Bio-Connect

BI-1622

Research Use Only
HY-150023
MedChem Express
Estimated Purity98.97%
Product group Chemicals
Molecular Weight508.53
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BI-1622
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    98.97%
  • Molecular Formula
    C26H24N10O2
  • Molecular Weight
    508.53
  • Scientific Description
    BI-1622 is an orally active, potent and highly selective HER2 (ERBB2) inhibitor, with an IC50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR. BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile.
  • SMILES
    O=C(N1CCN(CC1)C2=NC3=C(NC4=CC=C(C(C)=C4)OC5=CC6=NC=NN6C=C5)N=CN=C3C=N2)C=C
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200