Bictegravir-d4

MedChem Express

Bictegravir-d4

14

Research Use Only

C21H14D4F3N3O5

453.40

Bictegravir-d4 is a deuterium of Bictegravir (HY-17605). Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM[1].

O=C(NC([2H])(C1=C(C([2H])=C(C([2H])=C1F)F)F)[2H])C2=CN(C[C@]3(O[C@@]4([H])C[C@@]([H])(N3C5=O)CC4)[H])C5=C(C2=O)O

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