Bicuculline (methobromide)

MedChem Express

Bicuculline (methobromide) [66016-70-4]

10

66016-70-4

Research Use Only

C21H20BrNO6

462.29

Bicuculline methobromide is a selective GABAA Receptor antagonist with an IC 50 value of 3 microM. Bicuculline methobromide induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methobromide can be used in studies of epilepsy and other related psychiatric disorders [1] [2] .

C[N+]1([C@](C2=C(CC1)C=C3C(OCO3)=C2)([H])[C@@]4([H])C5=C(C6=C(OCO6)C=C5)C(O4)=O)C.[Br-]

12352200