(+)-Bicuculline (methochloride)

MedChem Express

(-)-Bicuculline (methochloride) [53552-05-9]

10

53552-05-9

C21H20ClNO6

417.84

(+)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABA A receptor antagonist. (+)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca 2+ -activated K + channels in various types of neurons [1] .

C[N+]1(C)[C@@H]([C@H]2OC(C3=C4OCOC4=CC=C32)=O)C5=C(C=C6C(OCO6)=C5)CC1.[Cl-]

12352200