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ProductsBack/Bikaverin [33390-21-5]
Chemical Structure
Chemical Structure
Chemical Structure

Bikaverin [33390-21-5]

Research Use Only
AG-CN2-0130
AdipoGen Life Sciences
CAS Number33390-21-5
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight382.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Bikaverin [33390-21-5]
  • Delivery Days Customer
    10
  • CAS Number
    33390-21-5
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C20H14O8
  • Molecular Weight
    382.3
  • Scientific Description
    Antibiotic [1]. Antiprotozoal [1]. Antifungal [2]. Anticancer [3-7]. ATP synthesis inhibitior [3, 4]. Haemolytic agent [5]. Antioomycete [8]. Spermidine-induced autoactivation inhibitor [9]. Plasma hyaluronan-binding protein (PHBP) inhibitor (active form) [9]. Review [10]. - Chemical. CAS: 33390-21-5. Formula: C20H14O8. MW: 382.3. Isolated from Fusarium sp. Antibiotic. Antiprotozoal. Antifungal. Anticancer. ATP synthesis inhibitior. Haemolytic agent. Antioomycete. Spermidine-induced autoactivation inhibitor. Plasma hyaluronan-binding protein (PHBP) inhibitor (active form). Review.
  • SMILES
    COC1=CC(C)=C2C(=O)C3=C(OC2=C1)C(O)=C1C(=O)C(OC)=CC(=O)C1=C3O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Bikaverin, an antibiotic from ibberella fujikoi, effective against Leishmania brasiliensis: J. Balan, et al.; Folia Microbiol. 15, 479 (1970)
  • Isolation and characterization of a fungal vacuolation factor (bikaverin): J.W. Cornforth, et al.; J. Chem. Soc. Perkin 16, 2786 (1971)
  • New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors: J. Fuska, et al.; Neoplasma 22, 335 (1975)
  • Effects of bikaverin on purine nucleotide synthesis and catabolism in Ehrlich ascites tumor cells in vitro: J.F. Henderson, et al.; Biochem. Pharmacol. 26, 1973 (1977)
  • Inhibition of mitochondrial functions by the antibiotics, bikaverin and duclauxine: L. Kovac, et al.; J. Antibiot. (Tokyo) 31, 616 (1978)
  • Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes: W.P. Norred, et al.; Food Chem. Toxicol. 30, 233 (1992)
  • Search for cell motility and angiogenesis inhibitors with potential anticancer activity: beauvericin and other constituents of two endophytic strains of Fusarium oxysporum: J. Zhan, et al.; J. Nat. Prod. 70, 227 (2007)
  • Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans: S.W. Son, et al.; J. Appl. Microbiol. 104, 692 (2008)
  • Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein: N. Nishimura, et al.; Biol. Pharm. Bull. 33, 1430 (2010)
  • Bikaverin production and applications: M.C. Limon, et al.; Appl. Microbiol. Biotechnol. 87, 21 (2010) (Review)