Biotin-PEG4-amino-t-Bu-DADPS-C6-azide [1260247-50-4]

MedChem Express

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide [1260247-50-4]

10

1260247-50-4

Research Use Only

95.0

C43H67N7O9SSi

886.18

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(NCC(C)(O[Si](C1=CC=CC=C1)(OCCCCCCN=[N+]=[N-])C2=CC=CC=C2)C)CCOCCOCCOCCOCCNC(CCCC[C@@H]3SC[C@]([C@]3([H])N4)([H])NC4=O)=O

-20°C

41115800