Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Protein (LRR-CM415B)

KACTUS

Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Protein (LRR-CM415B)

9

Research Use Only

Biotin

>95%

The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.

-20°C or -80°C,-80°C

12352202