Biotinylated Human CD96/TACTILE Protein (CD9-HM496B)

KACTUS

Biotinylated Human CD96/TACTILE Protein (CD9-HM496B)

9

Research Use Only

Biotin

>95%

The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

-20°C or -80°C,-80°C

12352202