Biotinylated Human CTLA-4/CD152 Protein (CTL-HM401B)

KACTUS

Biotinylated Human CTLA-4/CD152 Protein (CTL-HM401B)

9

Research Use Only

Biotin

>95%

Cytotoxic T-lymphocyte protein 4

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation - a phenomenon which is particularly notable in cancers. It acts as an off switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.

-20°C or -80°C,-80°C

12352202