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ProductsBack/Biotinylated Human HLA-A02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)

Biotinylated Human HLA-A02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)

MHC-HM411B
KACTUS
Protein IDP61769
Product group Proteins / Signaling Molecules
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More than 130 suppliers
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Overview

  • Supplier
    KACTUS
  • Product Name
    Biotinylated Human HLA-A02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Conjugate
    Biotin
  • Estimated Purity
    >95%
  • Protein IDP61769
  • Protein Name
    Beta-2-microglobulin
  • Scientific Description
    The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202