Biotinylated Human HLA-A02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)
MHC-HM411B
Protein IDP61769
Product group Proteins
Overview
- SupplierKACTUS
- Product NameBiotinylated Human HLA-A02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)
- Delivery Days Customer9
- CertificationResearch Use Only
- ConjugateBiotin
- Estimated Purity>95%
- Protein IDP61769
- Protein NameBeta-2-microglobulin
- Scientific DescriptionThe immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202