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Biotinylated Human Notch 1 Protein (NOT-HM401B)

NOT-HM401B
KACTUS
Protein IDP46531
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Biotinylated Human Notch 1 Protein (NOT-HM401B)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Protein IDP46531
  • Protein Name
    Neurogenic locus notch homolog protein 1
  • Scientific Description
    Human Notch-1 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes.Notch-1 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202