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Biotinylated Human Notch 2 Protein (NOT-HM402B)

NOT-HM402B
KACTUS
Protein IDQ04721
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Biotinylated Human Notch 2 Protein (NOT-HM402B)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Conjugate
    Biotin
  • Estimated Purity
    >95%
  • Protein IDQ04721
  • Protein Name
    Neurogenic locus notch homolog protein 2
  • Scientific Description
    Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch-2 is lethal, showing that not all functions overlap.Notch-2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202