Bio-Connect

Biotinylated Human TREM2 Protein (TRM-HM401B)

TRM-HM401B
KACTUS
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Biotinylated Human TREM2 Protein (TRM-HM401B)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Scientific Description
    TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202