Bis-sulfone-PEG3-Azide [1802908-01-5]

MedChem Express

Bis-sulfone-PEG3-Azide [1802908-01-5]

10

1802908-01-5

Research Use Only

99.42

C33H40N4O9S2

700.82

Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-sulfone-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(NCCOCCOCCOCCN=[N+]=[N-])C1=CC=C(C(C(CS(=O)(C2=CC=C(C)C=C2)=O)CS(=O)(C3=CC=C(C)C=C3)=O)=O)C=C1

-20°C

41115800