Bisindolylmaleimide I (free base) [GF-109203X; Goe 6850]

Bioss Antibodies

Bisindolylmaleimide I (free base) [GF-109203X; Goe 6850] [133052-90-1]

16

Research Use Only

>97%

Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM) [1]. Competetive inhibitor for the ATP-binding site of PKC [1]. Anti-inflammatory [2]. Binds to P-glycoprotein [3]. Telomerase activity inhibitor [4]. Potent glycogen synthase kinase-3 (GSK-3) inhibitor [5]. Necrosis inhibitor [6]. Blocks hERG potassium channels [7-9]. Promotes osteoblastogenesis in human mesenchymal stem cells [10].

-20°C

51202000