BIT-225

MedChem Express

BIT-225

5

Research Use Only

98.87

C16H15N5O

293.32

BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1 , especially in monocyte-derived macrophages ( EC 50 is 2.25 microM), without significant cytotoxicity (TC 50 is 284 microM) [1] .

O=C(C1=CC2=CC=CC(C3=CN(C)N=C3)=C2C=C1)NC(N)=N

2°C to 8°C

12352200