Bivamelagon

MedChem Express

Bivamelagon

5

Research Use Only

99.50

C35H53ClN4O4

629.27

Bivamelagon (MC-4R Agonist 2) is an orally active and BBB-penetrable MC4R agonist with EC50 values of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay), and a Ki of 65 nM. Bivamelagon can be used for the research of diseases such as obesity and diabetes[1].

O=C([C@H]1[C@H](C2=CC=C(C=C2)Cl)CN(C1)C(C)(C)C)N3[C@@H](C[C@@H](C3)N([C@@H]4CC[C@@H](CC4)C)C(C(C)C)=O)C(N5CCOCC5)=O

-20°C,2°C to 8°C

12352200