BL-1020 (mesylate)

MedChem Express

BL-1020 (mesylate)

5

Research Use Only

C26H37ClN4O5S2

585.18

BL-1020 mesylate is the mesylate salt form of BL-1020. BL-1020 mesylate is an antipsychotic agent. BL-1020 mesylate is inhibitor for dopamine receptor and serotonin receptor ( 5-HT receptor ), with K i of 0.066, 0.062 and 0.21 nM, for D2L, D2S and 5-HT2A receptors, respectively. BL-1020 mesylate is agonist for GABA A receptor with K i of 3.74 microM, and enhances the GABA release. BL-1020 mesylate exhibits high affinity with histamine receptor (K i is 0.47 nM). BL-1020 mesylate reduces Amphetamine-induced hyperactivity, with lower catalepsy and sedation. BL-1020 mesylate is blood-brain barrier penetrate [1] .

O=C(CCCN)OCCN1CCN(CCCN2C3=C(SC4=CC=C(C=C42)Cl)C=CC=C3)CC1.O=S(O)(C)=O

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