Blood Group Lewis a antibody [T174]

GeneTex

Blood Group Lewis a antibody [T174]

9

This antibody detects Lewis A (Type 1 chain) antigen and belongs to the BG-5 group of antibodies, one of a series of well-characterized murine monoclonal antibodies.

IHC-P: Use at a dilution of 1/40 or greater, for Biotin based detection systems. For optimal staining the primary antibody should be incubated 20-60 minutes at room temperature. Antigen retrieval is not essential. Optimal dilutions/concentrations should be determined by the end user.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

T174

0.1 mg/ml

Unconjugated

Mouse

IgG1

Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Human

2°C to 8°C

12352203