Cirtociclib

MedChem Express

BLU-222

5

Research Use Only

99.02

C15H17F2N7O2

365.34

Cirtociclib (BLU-222) is an orally active and highly selective CDK2 inhibitor. Cirtociclib disrupts Rb signaling and causes G1 arrest and apoptosis in CCNE1-amplified endometrial cancer cells [1] [2] [3] .

FC(OC1=CC(NC2=NC3=C(C=NN3CC4CCOCC4)N=C2)=NN1)F

-20°C,2°C to 8°C

12352200