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ProductsBack/BMI1 antibody

BMI1 antibody

Research Use Only
ORB66847
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetBMI1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    BMI1 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID648
  • Target name
    BMI1
  • Target description
    BMI1 proto-oncogene, polycomb ring finger
  • Target synonyms
    B lymphoma Mo-MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group RING finger protein 4; ring finger protein 51; RNF51
  • Host
    Rabbit
  • Protein IDP35226
  • Protein Name
    Polycomb complex protein BMI-1
  • Scientific Description
    Rabbit polyclonal to BMI1.BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required tomaintain the transcriptionally repressive state of many genes, including Hox genes, throughoutdevelopment. PcG PRC1 complex acts via chromatin remodeling and modification of histones; itmediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in itsexpressibility. In the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligaseactivity of RNF2/RING2.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203