BMP2 Polyclonal Antibody

Reddot Biotech

BMP2 Polyclonal Antibody

5

1 mg/ml

BMP2

bone morphogenetic protein 2

BDA2; BMP2A; bone morphogenetic protein 2; bone morphogenetic protein 2A; SSFSC; SSFSC1

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

-20°C

12352203