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BMPR1A/ALK-3, Human (HEK293, His)

Research Use Only
HY-P75594
MedChem Express
Protein IDP36894
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMPR1A/ALK-3, Human (152a.a, HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Protein IDP36894
  • Protein Name
    Bone morphogenetic protein receptor type-1A
  • Scientific Description
    BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues[1]. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis[2][3]. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders[4]. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (HEK293, His) is produced in HEK293 cells, with a C-terminal His-tags.
  • UNSPSC
    12352202