BMS-1166-N-piperidine-CO-N-piperazine

MedChem Express

BMS-1166-N-piperidine-CO-N-piperazine [2447066-14-8]

10

Research Use Only

BMS-1166-N-piperidine-CO-N-piperazine incorporates a ligand for PD-1/PD-L1 immune checkpoint, and a PROTAC linker. BMS-1166-N-piperidine-CO-N-piperazine can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183). PROTAC PD-1/PD-L1 degrader-1 inhibits PD-1/PD-L1 interaction with an IC 50 of 39.2 nM [1] .

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