BMS-214662 (hydrochloride)

MedChem Express

BMS-214662 (hydrochloride) [195981-08-9]

5

Research Use Only

BMS-214662 hydrochloride is an inhibitor of farnesyltransferase ( Farnesyl Transferase ). BMS-214662 hydrochloride can effectively block the localization and function of Ras proteins on the cell membrane by inhibiting the prenylation modification of Ras proteins, thereby exerting anti-tumor activity. The IC 50 value of BMS-214662 hydrochloride for H-Ras is 1.3 nM, and for K-Ras it is 8.4 nM. BMS-214662 hydrochloride can be used in the research of tumor diseases related to Ras [1] [2] .

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