BMS-394136

MedChem Express

BMS-394136

5

Research Use Only

C24H21Cl2FN4O

471.35

BMS-394136 (compound 1) is a potent inhibitor of Kv 1.5 , with an IC 50 of 0.05 microM. BMS-394136 is a selective IKur inhibitor. BMS-394136 dose-dependently prolongs atrial effective refractory period (AERP) and action potential duration (APD) without effecting ventricular effective refractory period (VERP). BMS-394136 can be used for acute atrial ischemia research [1] .

O=C(C1=C(NC2=CC=NN2[C@@H]1C3=CC(Cl)=C(C=C3)Cl)C)N4[C@@H](CCC4)C5=CC=C(C=C5)F

12352200