BMS-654457

MedChem Express

BMS-654457 [1004551-41-0]

10

1004551-41-0

Research Use Only

C36H37N5O4

603.71

BMS-654457 is a small-molecule, reversible inhibitor of factor XIa ( FXIa ), binding with human and rabbit FXIa with K i s of 0.2 and 0.42 nM, respectively.

NC(C1=CC=C(N[C@H](C2=CC(C3=CC=C(C(N)=O)C=C3C(O)=O)=CC(NC(CC(C)C)=O)=C2)C[C@]4(C)C5=CC=CC=C5)C4=C1)=N

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