BMS-748730

MedChem Express

BMS-748730 [910297-57-3]

5

910297-57-3

Research Use Only

C22H26ClN7O3S

504.00

BMS-748730 is an oral tyrosine kinase inhibitor. BMS-748730 inhibits tyrosine kinase activity by competing with the ATP binding site of the tyrosine kinase , which prevents the kinase from phosphorylating the substrate protein, thereby inhibiting signaling pathways associated with cell proliferation and tumor growth. BMS-748730 can be used in the study of certain types of cancer, including chronic myeloid leukemia (CML) [1] .

O=C(C1=CN=C(NC2=CC(N3CCN(CC3)CCO)=NC(C)=N2)S1)NC4=C(C)C=C(O)C=C4Cl

12352200