BMS-814580 [1197420-11-3]

TargetMol Chemicals

BMS-814580 [1197420-11-3]

86

Chemical

Research Use Only

BMS-814580

C24H19ClF2N2O4S

504.93

BMS-814580 is a potent and selective functional antagonist (Kb = 117 nM) of human MCHR1. BMS-814580 exhibits potent binding affinity (Ki = 17 nM) for human MCHR1. BMS-814580 also exhibits potent binding affinities for cynomolgus monkey and rat MCHR1 (Ki of 4.9 and 11.5 nM, respectively). MCHR1 antagonist demonstrates reduction in feeding and body weight in rats and mice.

3 years

O=C1C2=C(C=C(S2)C3=CC=C(Cl)C=C3)N=CN1C4=CC(OC)=C(OCC5(O)CC(F)(F)C5)C=C4

-20°C

12352200