BMS-986020 (sodium)

MedChem Express

BMS-986020 (sodium) [1380650-53-2]

10

1380650-53-2

99.41

C29H25N2NaO5

504.51

BMS-986020 (AM152) sodium is a high-affinity lysophosphatidic acid receptor 1 ( LPA1 ) antagonist [1] . BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC 50 s of 4.8 microM, 6.2 microM, and 7.5 microM for BSEP, MRP4, and MDR3, respectively [2] . BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF) [3] .

O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O[Na]

2°C to 8°C

12352200