BMS-986118 [1610562-74-7]

TargetMol Chemicals

BMS-986118 [1610562-74-7]

114

Chemical

Research Use Only

BMS-986118

C25H28ClF3N4O4

540.96

BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia.

3 years

C(C(O)=O)[C@@H]1N(N=C(C(F)(F)F)[C@H]1C)C2=CC=C(O[C@H]3[C@H](C)CN(CC3)C=4C=C(OC)N=CC4Cl)C=C2

-20°C

12352200