BMS-986172 [1808258-99-2]

TargetMol Chemicals

BMS-986172 [1808258-99-2]

16

Chemical

Research Use Only

BMS-986172

C24H22F7N7O3

589.47

BMS-986172 is an orally active, highly selective inhibitor of MGAT2, with inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM for mouse MGAT2 (mMGAT2). It exhibits an in vitro half-life (T1/2) greater than 120 minutes and is known to decrease food intake and body weight. This compound is promising for research in metabolic disorders, including obesity and non-alcoholic steatohepatitis (NASH) [1].

3 years

[C@](F)(F)(F)[C@]1(CC(=C(C(=O)N1)N2N=NNC2=O)C3=NN(CC4CC4)C=C3)C5=C(F)C=C(OCCCC(F)(F)F)C=C5

-20°C

12352200