BMY 7378

MedChem Express

BMY 7378 [21102-95-4]

10

21102-95-4

99.92

C22H33Cl2N3O3

458.42

BMY 7378 is a selective antagonist of alpha 1D -adrenoceptor (alpha 1D -AR). BMY 7378 binds to membranes expressing the cloned rat alpha 1D -AR with a >100-fold higher affinity ( K i =2 nM) than binding to either the cloned rat alpha 1A -AR (K i =800 nM) or the hamster alpha 1B -AR ( K i =600 nM). BMY 7378 is a 5-HT 1A receptor partial agonist [1] [2] .

O=C(N(CCN1CCN(C2=CC=CC=C2OC)CC1)C(C3)=O)CC43CCCC4.[H]Cl.[H]Cl

2°C to 8°C

12352200